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Latest announcements

January 2026

InterAx and Alveus Therapeutics announce a strategic research and licensing agreement

InterAx Biotech and Alveus Therapeutics announced a strategic research collaboration and licensing agreement, signed on 2 June 2025, to develop a differentiated small-molecule candidate for metabolic disease. The agreement includes an upfront payment and eligibility for development, regulatory and commercial milestones. Alveus was founded by former Novo Nordisk and Eli Lilly executives.

October 2025

InterAx appoints Andrew Roberts as Chief Executive Officer

Andrew Roberts joined InterAx as CEO to lead the company's transition from a drug discovery technology pioneer to a developer of differentiated GPCR drug candidates. He brings more than 20 years of biopharmaceutical R&D and portfolio leadership at Novartis, Sandoz and Biogen Idec, and was Chief Portfolio Officer at Alvotech.

November 2023 · Grant

InterAx selected for a Horizon Europe EIC Pathfinder consortium

InterAx was selected as a participant in a Horizon Europe EIC Pathfinder project developing new methods to characterize the intracellular effects of drug candidates. The reviewers recognized the company's use of mathematical models and machine learning to design drugs with targeted cellular effects.

October 2023

Mark Levick, MD PhD, joins the InterAx Board of Directors

Dr Mark Levick, former CEO of Alvotech and former Senior Vice President of Global Drug Discovery at Novartis, joined the InterAx board. He oversaw R&D programs that resulted in thirteen drug approvals, five of them first-in-class, and advises the company as it advances its pipeline toward clinical trials.

Publications

  • Höppner J et al. · 2026
    Disease-causing helix-8 mutations reprogram parathyroid hormone receptor-1 effector selectivity
  • Lopez-Balastegui M et al. · 2026
    The GPCRVP score reliably predicts the impact of GLP1R human variants on receptor function
  • Lindquist P et al. · 2026
    GLP-1R and GIPR crosstalk modulates insulinotropic signaling pathways
  • Steiner WP et al. · 2026
    Structural mechanism for noncanonical GPCR signaling in the Hedgehog pathway
    Nature Structural & Molecular Biology doi:10.1038/s41594-026-01800-z
  • Balfe EM et al. · 2026
    Rare variant in intracellular loop-2 alters the spatial distribution and transducer coupling selectivity of the ghrelin receptor
    Molecular Pharmacology doi:10.1016/j.molpha.2026.100119
  • Berghella A et al. · 2025
    Type-1 Cannabinoid Receptor Promiscuous Coupling: Computational Insights into Receptor-G Protein Interaction Dynamics
    International Journal of Molecular Sciences doi:10.3390/ijms262411905
  • Miranda-Azpiazu P et al. · 2025
    Distinctive patterns of G protein coupling induced by the structurally similar 5-HT2A receptor ligands ketanserin and altanserin in human prefrontal cortex
    Molecular Pharmacology doi:10.1016/j.molpha.2025.100075
  • Ji JS et al. · 2025
    An arginine switch drives the stepwise activation of β-arrestin by CXCR7
  • Morales-Pastor A et al. · 2025
    Multiple intramolecular triggers converge to preferential G protein coupling in the CB2R
    Nature Communications doi:10.1038/s41467-025-60003-0
  • Aranda-García D et al. · 2025
    Large scale investigation of GPCR molecular dynamics data uncovers allosteric sites and lateral gateways
    Nature Communications doi:10.1038/s41467-025-57034-y
  • Heitzler D et al. · 2012
    Competing G protein-coupled receptor kinases balance G protein and β-arrestin signaling
    Molecular Systems Biology The foundational model behind Deep Signal. doi:10.1038/msb.2012.22